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BPS Pharmacotherapy (Part1 and Part2) Sample Questions:

1. A 13-year-old boy who has asthma, weight 32kg, height 150cm, takes inhaled salmeterol one puff twice daily and inhaled fluticasone 2 puffs twice daily. The patient must stop participation in physical education classes after a few minutes due to shortness of breath. To allow the patient to participate longer, the most effective measure would be to add which of the following?

A) An extra dose of inhaled salmeterol 30-60 minutes before class
B) An extra dose of inhaled fluticasone 1-2 hours before class
C) Inhaled albuterol 15 minutes before class
D) Inhaled cromolyn 30-60 minutes prior to class

2. A 65-year-old man with heart failure is currently receiving digoxin, lisinopril, furosemide, and carvedilol. He is in normal sinus rhythm and is hemodynamically stable. His left ventricular ejection fraction is 30%. Which of the following statements best describes the role of digoxin therapy in this patient?

A) It can improve mortality.
B) It can be synergistic with carvedilol.
C) It can be safely discontinued.
D) It can decrease the risk of hospitalization.

3. A patient is started on ledipasvir-sofosbuvir. What would be the best indicator of treatment response?

A) HCV RNA below the lower limit of quantification
B) Absence of alpha-fetoprotein
C) ALT less than three times the upper limit of normal
D) Absence of cryoglobulinemia

4. A 59-year-old patient with a diagnosis of deep vein thrombosis is anticoagulated with enoxaparin 1 mg/kg every 12 hours and warfarin 5 mg daily. On the third day of therapy, his INR
= 2.2. The patient is symptomatically improved. Which of the following is the most appropriate management of this patient?

A) Continue enoxaparin and warfarin.
B) Discontinue enoxaparin and increase warfarin.
C) Discontinue enoxaparin and continue warfarin.
D) Continue enoxaparin and hold Warfarin.

5. The Randomized Aldactone Evaluation Study (RALES) yielded the following results:
* Placebo death rate: 386/841
* Spironolactone death rate: 284/822
Given these data, which of the following is the relative risk reduction for death with spironolactone, in comparison with placebo?

A) 31%
B) 24%
C) 11%
D) 45%

Solutions: